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Article

Adaptive evolutionary walks require neutral intermediates in RNA fitness landscapes.

Theoretical population biology - 1 Jan 2000

Rendel Mark D

Abstract excerpt

In RNA fitness landscapes with interconnected networks of neutral mutations, neutral precursor mutations can play an important role in facilitating the accessibility of epistatic adaptive mutant combinations. I use an exhaustively surveyed fitness landscape model based on short sequence RNA genot...

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Identifiers

PMID: 20937293
DOI: 10.1016/j.tpb.2010.10.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20937293-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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