Article
An NF1-like protein functions as a repressor of the von Willebrand factor promoter.
The Journal of biological chemistry - 30 Aug 1996
Jahroudi N, Ardekani A M, Greenberger J S
Abstract excerpt
The expression of the von Willebrand factor (vWf) gene is restricted to endothelial cells and megakaryocytes. We have previously reported the identification of a region of the vWf gene that regulates its cell-type-specific expression in cell culture. This region (spanning nucleotides -487 to +247) consists of a core promoter (spanning nucleotides -90 to +22), a positive regulatory region (spanning nucleotides...
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