Article
Characterization of cis-regulatory elements of the vascular endothelial growth inhibitor gene promoter.
The Biochemical journal - 15 Jun 2005
Xiao Qingli, Hsu Chung Y, Chen Hong, Ma Xiucui, Xu Jan, Lee Jin-Moo
Abstract excerpt
VEGI (vascular endothelial growth inhibitor), a member of the tumour necrosis factor superfamily, has been reported to inhibit endothelial cell proliferation, angiogenesis and tumour growth. We identified and cloned approx. 2.2 kb of the VEGI promoter from mouse cerebral endothelial cells. The promoter contained an atypical TATA-box-binding protein sequence TAAAAAA residing at -32/-26 relative to the...
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