Article
The heparin binding PECAM-1 adhesion molecule is expressed by CD34+ hematopoietic precursor cells with early myeloid and B-lymphoid cell phenotypes.
Blood - 1 Nov 1993
Watt S M, Williamson J, Genevier H, Fawcett J, Simmons D L, Hatzfeld A, Nesbitt S A, Coombe D R
Abstract excerpt
The platelet-endothelial cell adhesion molecule-1 (PE-CAM-1), defined by the CD31 monoclonal antibody (MoAb), was initially described as a cell-cell adhesion molecule mediating both homotypic and heterotypic adhesion. In this report, we show that enriched CD34+ human hematopoietic progenitor cell populations, containing early myeloid, erythroid, and multipotential progenitor cells, are CD31+. Analyses of CD34+...
Topics
- Adult
- Animals
- Antigens, CD
- Antigens, CD34
- Antigens, Differentiation, Myelomonocytic
- B-Lymphocytes
- Base Sequence
- Bone Marrow
- Bone Marrow Cells
- Cell Adhesion Molecules
- Cell Line