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Article

Chemostat selection of an Escherichia coli mutant containing permease with enhanced lactose affinity.

Biochemical and biophysical research communications - 16 Jul 1996

Tsen S D, Lai S C, Pang C P, Lee J I, Wilson T H

Abstract excerpt

Chemostats supplied with limited lactose were used to ask whether it was possible to generate and isolate any mutant of Escherichia coli lactose permease which allowed cells to grow faster. The permease and beta-galactosidase activities of the chemostat culture initially rose together to reach a plateau. After 30 days, the former underwent a second increase alone. From this culture, a faster-growing mutant was...

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PMID: 8702394
DOI: 10.1006/bbrc.1996.1032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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