Article
[The capacity of avirulent forms of Francisella tularensis for dissemination and proliferation in the host body].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000
Tsimbalistova M V, Pavlovich N V, Sorokin V M, Tynkevich N K
Abstract excerpt
In this investigation isogenic avirulent variants obtained from F. tularensis standard virulent strain 503 were used. The capsule-deficient variants (cap-) were shown to have no species-specific capsular antigens and to be capable of producing R-LPS having no the polysaccharide part of the molecules. The capsule-defective forms (cap +/- ) were found to synthesize capsular antigens and S-LPS whose polysaccharide...
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