Article
[Pleiotropic nature of mutation of resistance to 2,3,5-triphenyl- tetrazolium chloride of Francisella tularensis].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] - 1 Apr 1992
Pavlovich N V, Danilevskaia G I, Khodova V A, Ryzhko I V, Mishan'kin B N
Abstract excerpt
Natural strains of F. tularensis were characterized by sensitivity to 2,3,5-triphenyl tetrazolium chloride (TTC). Development of TTC resistance in the cells of F. tularensis was accompanied by changes in the biological properties of the culture, i.e. the colony morphology, antigenic structure, vi...
Topics
- Animals
- Disease Models, Animal
- Drug Resistance, Microbial
- Francisella tularensis
- Gene Expression Regulation, Bacterial
- In Vitro Techniques
- Mice
- Microbial Sensitivity Tests
- Models, Genetic
- Mutation
- Phenotype
- R Factors
- Tetrazolium Salts
- Tularemia