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Article

[The characteristics of the biological properties of capsule-free variants of Francisella tularensis].

Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000

Pavlovich N V, Mishan'kin B N, Shimaniuk N Ia, Ryzhkova V V, Danilevskaia G I, Mikhalevich R V

Abstract excerpt

Comparative study of the properties of initial capsular (cap+) and non-capsular (cap-) F. tularensis strains has revealed that the non-capsular variants have their specific biological features. The characteristic features of these variants are avirulence and inability to produce an immunogenic effect in sensitive laboratory animals. Cap- mutants, depending on the method of their obtaining, may exhibit different...

Topics

Animals
Anti-Bacterial Agents
Bacterial Capsules
Francisella tularensis
Genetic Variation
Guinea Pigs
Macrophages, Peritoneal
Mice
Microbial Sensitivity Tests
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virulence

Source

Identifiers

PMID: 8067085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8067085-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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