Article
[The isolation of capsule-free variants of Francisella tularensis].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000
Pavlovich N V, Mishan'kin B N, Danilevskaia G I, Khodova V A, Ryzhkova V V, Tsimbalistova M I, Sukhar' V V
Abstract excerpt
New methods (selection in medium T with 20% Tween-80, inducing mutations leading to the appearance of resistance to triphenyl tetrazolium chloride or indoxyl phosphate) helped create a collection of F. tularensis stable non-capsular variants from strains of different subspecies. The characteristic features of all F. tularensis cap- variants include inability to serologic tests with erythrocytic diagnosticum, the...
Topics
- Antigens, Bacterial
- Bacterial Capsules
- Bacteriological Techniques
- Culture Media
- Francisella tularensis
- Mutation
- Phenotype
- Serial Passage
- Virulence