Article
Determinants of activation by complement of group II phospholipase A2 acting against Escherichia coli.
Infection and immunity - 1 Jul 1996
Madsen L M, Inada M, Weiss J
Abstract excerpt
Prompt killing of many strains of Escherichia coli during phagocytosis in vitro by isolated polymorphonuclear leukocytes (PMN) requires the presence of nonlethal doses of nonimmune serum (B. A. Mannion, J. Weiss, and P. Elsbach, J. Clin. Invest. 86:631-641, 1990). Because this requirement is bypassed in a phospholipase A (PLA)-rich mutant (pldA ) of E. coli, we have examined the effect of serum on bacteria]...
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