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Article

Lipoprotein Release by Bacteria: Potential Factor in Bacterial Pathogenesis

1 Nov 1998

Abstract excerpt

Lipoprotein (LP) is a major component of the outer membrane of bacteria in the family Enterobacteriaceae. LP induces proinflammatory cytokine production in macrophages and lethal shock in LPS-responsive and -nonresponsive mice. In this study, the release of LP from growing bacteria was investigated by immuno-dot blot analysis. An immuno-dot blot assay that could detect LP at levels as low as 100 ng/ml was...

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PMID: 9784522
DOI: 10.1128/iai.66.11.5196-5201.1998

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