Article
Pseudomonas aeruginosa hemolytic phospholipase C suppresses neutrophil respiratory burst activity.
Infection and immunity - 1 May 1999
Terada L S, Johansen K A, Nowbar S, Vasil A I, Vasil M L
Abstract excerpt
Pseudomonas aeruginosa is a persistent pathogen in the airways of patients with cystic fibrosis or bronchiectasis from other causes and appears to have evolved strategies to survive the inflammatory response of the host. We hypothesized that the secreted hemolytic phospholipase C (PLC) of P. aeruginosa (PlcHR) would decrease neutrophil respiratory burst activity. We found that while intact wild-type P. aeruginosa...
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