Article
Prc contributes to Escherichia coli evasion of classical complement-mediated serum killing.
Infection and immunity - 1 Oct 2012
Wang Chin-Ya, Wang Shainn-Wei, Huang Wen-Chun, Kim Kwang Sik, Chang Nan-Shan, Wang Ying-Hsiang, Wu Meng-Hsing, Teng Ching-Hao
Abstract excerpt
Escherichia coli is a common Gram-negative organism that causes bacteremia. Prc, a bacterial periplasmic protease, and its homologues are known to be involved in the pathogenesis of Gram-negative bacterial infections. The present study examined the role of Prc in E. coli bacteremia and characterized the ability of the prc mutant of the pathogenic E. coli strain RS218 to cause bacteremia and survive in human...
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