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Article

Clonal analysis of human breast cancer by means of the polymerase chain reaction.

Cancer research - 1 Dec 1992

Noguchi S, Motomura K, Inaji H, Imaoka S, Koyama H

Abstract excerpt

Clonality of human breast cancer was analyzed in small DNA samples prepared from cryostat sections, by means of the polymerase chain reaction (PCR). The method used for clonal analysis was based on restriction fragment length polymorphism of X-chromosome-linked phosphoglycerokinase (PGK) gene and on the differential methylation of the PGK gene due to random inactivation of one of two X-chromosomes by methylation...

Topics

Alleles
Base Sequence
Breast
Breast Neoplasms
DNA, Neoplasm
Female
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Restriction Mapping
X Chromosome

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PMID: 1423305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1423305-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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