Article
Clonal analysis of human gynecologic cancers by means of the polymerase chain reaction.
International journal of cancer - 15 Aug 1994
Sawada M, Azuma C, Hashimoto K, Noguchi S, Ozaki M, Saji F, Tanizawa O
Abstract excerpt
Clonality of human gynecologic cancers was analyzed in small DNA samples prepared from cryostat sections, by means of the polymerase chain reaction (PCR). The method used for clonal analysis was based on restriction fragment length polymorphism of the X-chromosome-linked phosphoglycerokinase (PGK) gene and on the differential methylation of the PGK gene due to random inactivation of 1 of 2 X-chromosomes by...
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