Article
Detection of clonality and genetic alterations in endometrial pipelle biopsy and its surgical specimen counterpart.
Laboratory investigation; a journal of technical methods and pathology - 1 Jan 1997
Esteller M, García A, Martínez-Palones J M, Xercavins J, Reventós J
Abstract excerpt
Carcinoma of the endometrium is the most frequently diagnosed gynecologic malignancy in the western world. Because endometrial carcinoma is monoclonal in origin, the small samples obtained in endometrial pipelle biopsies can be used in PCR clonal studies to distinguish cancerous from noncancerous lesions. The method used for clonal analysis was based on RFLP of the X chromosome-linked phosphoglycerokinase gene...
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