Article
Functional characteristics of a variant thyrotropin receptor.
European journal of biochemistry - 1 Jun 1996
Tonacchera M, Cetani F, Costagliola S, Van Sande J, Refetoff S, Vassart G
Abstract excerpt
A claim has been made that a variant of the human thyrotropin receptor in which Pro52 is replaced by Thr ([Thr52]thyrotropin receptor) is associated with autoimmune thyroid diseases and displays increased responsiveness to thyrotropin. We have analysed the functional characteristics of this variant receptor. Equivalent numbers of of the wild type and of the variant thyrotropin receptor, measured both by...
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