Article
A variant of the human corticotropin-releasing factor (CRF) receptor: cloning, expression and pharmacology.
Biochemical and biophysical research communications - 30 Dec 1994
Ross P C, Kostas C M, Ramabhadran T V
Abstract excerpt
A variant of the human corticotropin-releasing factor receptor has been characterized. The variant has a 40-amino-acid deletion in the amino-terminal domain of the receptor and is the only form of this receptor detectable in the individual from which it was isolated. In contrast to the high affinity expressed by the normal human CRF receptor, the receptor variant fails to bind [125I]oCRF with high affinity in...
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