Polymorphism of a variant human thyrotropin receptor (hTSHR) gene.

doi:10.1089/thy.1994.4.147

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Article

Polymorphism of a variant human thyrotropin receptor (hTSHR) gene.

Thyroid : official journal of the American Thyroid Association - 1 Jan 1994

Sunthornthepvarakul T, Hayashi Y, Refetoff S

Abstract excerpt

Sequencing of the human thyrotropin receptor (hTSHR) gene using genomic DNA from peripheral blood leukocytes revealed a substitution of nucleotide 253 in the cDNA sequence. The replacement of the wild-type cytosine-253 to adenine results in the replacement of the wild-type Pro at codon 52 (CCC) w...

Topics

Base Sequence
DNA, Complementary
Female
Gene Amplification
Genetic Variation
Genotype
Humans
Male
Molecular Sequence Data
Pedigree
Polymerase Chain Reaction
Polymorphism, Genetic
Receptors, Thyrotropin

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