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Article

Developmentally regulated gene expression of thrombomodulin in postimplantation mouse embryos

1 Jul 1996

Abstract excerpt

Embryonic lethality of thrombomodulin-deficient mice has indicated an essential role for this regulator of blood coagulation in murine development. Here, the embryonic expression pattern of thrombomodulin was defined by surveying beta-galactosidase activity in a mouse strain in which the reporter gene was placed under the regulatory control of the endogenous thrombomodulin promoter via homologous recombination in...

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PMID: 8681807
DOI: 10.1242/dev.122.7.2271

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