Article
Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing.
Development (Cambridge, England) - 1 Jul 1996
Burke R, Basler K
Abstract excerpt
The mammalian growth factor TGFbeta negatively regulates cell proliferation in various systems. Here we provide evidence that another TGFbeta superfamily member, Drosophila Decapentaplegic (Dpp), stimulates cell proliferation. In the developing wing blade, somatic clones lacking the Dpp receptors...
Topics
- Animals
- Cell Division
- Clone Cells
- Drosophila
- Drosophila Proteins
- Embryo, Nonmammalian
- Gene Expression Regulation, Developmental
- Insect Hormones
- Phenotype
- Receptors, Transforming Growth Factor beta
- Recombination, Genetic
- Signal Transduction
- Transforming Growth Factor beta
- Veins
- Wings, Animal