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Article

Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing.

Development (Cambridge, England) - 1 Jul 1996

Burke R, Basler K

Abstract excerpt

The mammalian growth factor TGFbeta negatively regulates cell proliferation in various systems. Here we provide evidence that another TGFbeta superfamily member, Drosophila Decapentaplegic (Dpp), stimulates cell proliferation. In the developing wing blade, somatic clones lacking the Dpp receptors Punt or Thick veins (Tkv), or lacking Schnurri, a transcription factor involved in Dpp signal interpretation, fail to...

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Identifiers

PMID: 8681806
DOI: 10.1242/dev.122.7.2261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing.PMID 8681806Read ↗

An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo.Semantic proximity Read ↗

punt and schnurri regulate a somatically derived signal that restricts proliferation of committed progenitors in the germline.Semantic proximity Read ↗

Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis.Semantic proximity Read ↗

Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic.Semantic proximity Read ↗

Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1.Semantic proximity Read ↗

schnurri is required for dpp-dependent patterning of the Drosophila wing.Semantic proximity Read ↗

Formation of the long range Dpp morphogen gradient.Semantic proximity Read ↗

Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels.Semantic proximity Read ↗

Genetic analysis of punt, a type II Dpp receptor that functions throughout the Drosophila melanogaster life cycle.Semantic proximity Read ↗

Characterization and relationship of Dpp receptors encoded by the saxophone and thick veins genes in Drosophila.Semantic proximity Read ↗

The Drosophila schnurri gene acts in the Dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human MBP family.Semantic proximity Read ↗

Dynamics of Dpp signaling and proliferation control.Semantic proximity Read ↗

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