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Escherichia coli aminodeoxychorismate synthase: analysis of pabB mutations affecting catalysis and subunit association.

Biochimica et biophysica acta - 7 Jun 1996

Rayl E A, Green J M, Nichols B P

Abstract excerpt

p-Aminobenzoic acid (PABA), an essential component of the vitamin folic acid, is derived from the aromatic branch-point precursor chorismate in two steps. 4-Amino-4-deoxychorismate (ADC) synthase converts chorismate and glutamine to ADC and glutamate, and is composed of two subunits, PabA and PabB. While various experiments have suggested that PabA and PabB act as a complex, attempts to isolate the intact complex...

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PMID: 8679677
DOI: 10.1016/0167-4838(96)00029-5

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