Article
Folate synthesis in plants: the last step of the p-aminobenzoate branch is catalyzed by a plastidial aminodeoxychorismate lyase.
The Plant journal : for cell and molecular biology - 1 Nov 2004
Basset Gilles J C, Ravanel Stéphane, Quinlivan Eoin P, White Ruth, Giovannoni James J, Rébeillé Fabrice, Nichols Brian P, Shinozaki Kazuo, Seki Motoaki, Gregory Jesse F, Hanson Andrew D
Abstract excerpt
In plants, the last step in the synthesis of p-aminobenzoate (PABA) moiety of folate remains to be elucidated. In Escherichia coli, this step is catalyzed by the PabC protein, a beta-lyase that converts 4-amino-4-deoxychorismate (ADC)--the reaction product of the PabA and PabB enzymes--to PABA and pyruvate. So far, the only known plant enzyme involved in PABA synthesis is ADC synthase, which has fused domains...
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