Article
Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes.
Archives of virology - 1 Jan 1996
Hunter N, Foster J D, Goldmann W, Stear M J, Hope J, Bostock C
Abstract excerpt
Natural scrapie in a closed flock of South Country Cheviot sheep has resulted in 45 deaths between 1986 and 1995. Of these cases, 35 sheep have been analysed for disease-linked PrP gene polymorphisms and all encode valine at codon 136 on at least one allele with 77% homozygous (VV136) and 23% val...
Topics
- Animals
- Female
- Genotype
- Haplotypes
- Lymphocytes
- PrPSc Proteins
- Pregnancy
- Pregnancy Complications
- Scrapie
- Sheep
