Left ventricular size, mass, and function in relation to angiotensin-converting enzyme gene polymorphism in humans.

doi:10.1152/ajpheart.1994.267.3.H1107

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Article

Left ventricular size, mass, and function in relation to angiotensin-converting enzyme gene polymorphism in humans.

The American journal of physiology - 1 Sept 1994

Kupari M, Perola M, Koskinen P, Virolainen J, Karhunen P J

Abstract excerpt

Angiotensin-converting enzyme (ACE) exhibits genetic variation related to insertion/deletion (I/D) polymorphism in intron 16 of the ACE gene. The DD genotype results in high ACE activity and is overrepresented in diseases characterized by left ventricular (LV) hypertrophy and dysfunction. We stud...

Topics

Adult
Cardiomyopathies
Echocardiography
Female
Gene Deletion
Genotype
Heart Ventricles
Humans
Male
Peptidyl-Dipeptidase A
Polymorphism, Genetic
Ventricular Function, Left

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