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Article

Left ventricular size, mass, and function in relation to angiotensin-converting enzyme gene polymorphism in humans.

The American journal of physiology - 1 Sept 1994

Kupari M, Perola M, Koskinen P, Virolainen J, Karhunen P J

Abstract excerpt

Angiotensin-converting enzyme (ACE) exhibits genetic variation related to insertion/deletion (I/D) polymorphism in intron 16 of the ACE gene. The DD genotype results in high ACE activity and is overrepresented in diseases characterized by left ventricular (LV) hypertrophy and dysfunction. We studied whether the ACE gene polymorphism predicts LV mass or function in the absence of heart disease. Polymerase chain...

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Source

Identifiers

PMID: 8092275
DOI: 10.1152/ajpheart.1994.267.3.H1107

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Left ventricular size, mass, and function in relation to angiotensin-converting enzyme gene polymorphism in humans.PMID 8092275Read ↗

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Angiotensin-converting enzyme polymorphism in healthy young subjects: relationship to left ventricular mass and functions.Semantic proximity Read ↗

Lack of association of angiotensin-converting enzyme and angiotensinogen genes polymorphisms with left ventricular structure in young normotensive men.Semantic proximity Read ↗

Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass.Semantic proximity Read ↗

Lack of association between ACE gene polymorphism and left ventricular hypertrophy in essential hypertension.Semantic proximity Read ↗

Insertion/deletion polymorphism in the angiotensin-converting enzyme gene affects heart weight.Semantic proximity Read ↗

Left ventricular size, mass and function in relation to angiotensin-converting enzyme gene and angiotensin-II type 1 receptor gene polymorphisms in patients with coronary artery disease.Semantic proximity Read ↗

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Absence of Association or Genetic Linkage between the Angiotensin-Converting–Enzyme Gene and Left Ventricular MassSemantic proximity Read ↗

Usefulness of the I/D angiotensin-converting enzyme genotype for detecting the risk of left ventricular hypertrophy in pharmacologically treated hypertensive men.Semantic proximity Read ↗

Left ventricular hypertrophy with exercise and ACE gene insertion/deletion polymorphism: a randomized controlled trial with losartan.Semantic proximity Read ↗

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