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Article

Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype.

Journal of virology - 1 Jul 1996

Ray R B, Lagging L M, Meyer K, Ray R

Abstract excerpt

We have previously demonstrated that hepatitis C virus (HCV) core protein regulates cellular protooncogenes at the transcriptional level; this observation implicates core protein in the alteration of normal hepatocyte growth. In the present study, the transforming potential of the HCV core gene was investigated by using primary rat embryo fibroblast (REF) cells which were transfected with or without cooperative...

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Identifiers

PMID: 8676467
DOI: 10.1128/JVI.70.7.4438-4443.1996
PMCID: PMC190377

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Source receipt: pubmed, retrieved 7 Sept 2026.

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