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Article

A yeast protein that bidirectionally affects nucleocytoplasmic transport.

Journal of cell science - 1 Jan 1995

Singleton D R, Chen S, Hitomi M, Kumagai C, Tartakoff A M

Abstract excerpt

We have identified a temperature-sensitive mutant of Saccharomyces cerevisiae (npl3) that accumulates polyadenylated RNA in the nucleus at 37 degrees C, as judged by in situ hybridization. The strong nuclear signal is not simply due to increased cytoplasmic turnover of mRNA, as reincubation at 37 degrees C with an RNA polymerase inhibitor shows no diminution in the in situ signal. Over several hours at 37 degrees...

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PMID: 7738104
DOI: 10.1242/jcs.108.1.265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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A yeast protein that bidirectionally affects nucleocytoplasmic transport.PMID 7738104Read ↗

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