Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development.

Developmental biology - 1 Jun 2015

Klimova Lucie, Antosova Barbora, Kuzelova Andrea, Strnad Hynek, Kozmik Zbynek

Abstract excerpt

Genetic studies of the last decades strongly indicated that generation of particular retinal cell types is governed by gene regulatory networks of transcription factors and their target genes. The paired and homeodomain transcription factor Pax6 plays a pivotal role in retinal development as its inactivation in the retinal progenitor cell population leads to abolished differentiation of all retinal cell types....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Eye Proteins
Share to In Situ Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Paired Box Transcription Factors

Share to PAX6 Transcription Factor

Share to Retina

Share to Retinal Cone Photoreceptor Cells

Share to Sequence Homology, Nucleic Acid

Share to Stem Cells

Source

Identifiers

PMID: 25794677
DOI: 10.1016/j.ydbio.2015.02.023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development.PMID 25794677Read ↗

Onecut1 and Onecut2 redundantly regulate early retinal cell fates during developmentSemantic proximity Read ↗

Onecut 1 and Onecut 2 are potential regulators of mouse retinal developmentSemantic proximity Read ↗

Dose-dependent regulation of horizontal cell fate by Onecut family of transcription factors.Semantic proximity Read ↗

The roles of Pax6 in the cornea, retina, and olfactory epithelium of the developing mouse embryo.Semantic proximity Read ↗

Molecular description of eye defects in the zebrafish Pax6b mutant, sunrise, reveals a Pax6b-dependent genetic network in the developing anterior chamber.Semantic proximity Read ↗

Otx2 and Oc1 directly regulate the transcriptional program of cone photoreceptor developmentSemantic proximity Read ↗

PAX6 and congenital eye malformations.Semantic proximity Read ↗

PAX6 in sensory development.Semantic proximity Read ↗

Six3 and Six6 jointly regulate the identities and developmental trajectories of multipotent retinal progenitor cells in the mouse retinaSemantic proximity Read ↗

Her6 and Prox1 are novel regulators of photoreceptor regeneration in the zebrafish retinaSemantic proximity Read ↗

Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis.Semantic proximity Read ↗

Horizontal Cells, the Odd Ones Out in the Retina, Give Insights into Development and DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.