Suppression of heterochromatic gene variegation can be used to distinguish and characterize E(var) genes potentially important for chromosome structure in Drosophila melanogaster.

doi:10.1007/s00438-001-0633-6

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Article

Suppression of heterochromatic gene variegation can be used to distinguish and characterize E(var) genes potentially important for chromosome structure in Drosophila melanogaster.

Molecular genetics and genomics : MGG - 1 Feb 2002

Weiler K S, Wakimoto B T

Abstract excerpt

Hundreds of genic modifiers of position effect variegation (PEV) have been isolated in Drosophila melanogaster with a view to identifying genes important for chromosome structure. Here we propose a supplementary genetic screen to pinpoint candidate genes that are most likely to function in chromosome organization, within the enhancer of variegation [E(var)] class of modifiers. Our strategy takes advantage of the...

Topics

Animals
Chromosomes
Drosophila melanogaster
Eye
Gene Expression Regulation
Genes, Insect
Heterochromatin
Larva
Mutation
Salivary Glands

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Open in PubMed

Identifiers

PMID: 11862486
DOI: 10.1007/s00438-001-0633-6

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