Article
Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic mice.
The EMBO journal - 17 Jun 1996
Wilson J B, Bell J L, Levine A J
Abstract excerpt
The Epstein-Barr virus (EBV) nuclear antigen-1 (EBNA-1) is a pleiotropic protein which has been characterized extensively both biochemically and functionally. It is the only one of the identified latent protein-encoding genes to be consistently expressed in viral-associated endemic Burkitt's lymphoma cells. As such, it is the only candidate viral protein to possibly perform a maintenance function in the tumour...
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