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Article

Critical role of EBNA1-specific CD4+ T cells in the control of mouse Burkitt lymphoma in vivo

16 Aug 2004

Abstract excerpt

CD4 + T cells play important roles in orchestrating host immune responses against cancer and infectious diseases.Although EBV-encoded nuclear antigen 1-specific (EBNA1-specific) CD4 + T cells have been implicated in controlling the growth of EBV-associated tumors such as Burkitt lymphoma (BL) in vitro, direct evidence for their in vivo function remains elusive due to the lack of an appropriate experimental BL...

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PMID: 15314691
DOI: 10.1172/jci22053

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