Article
Alloimmunity to human endothelial cells derived from cord blood progenitors.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2007
Suárez Yajaira, Shepherd Benjamin R, Rao Deepak A, Pober Jordan S
Abstract excerpt
There is considerable interest in exploiting circulating endothelial progenitor cells (EPCs) for therapeutic organ repair. Such cells may be differentiated into endothelial cells (ECs) in vitro and then expanded for use in tissue engineering. Vessel-derived ECs are variably immunogenic, depending upon tissue source, and it is unknown whether ECs derived from cord blood EPCs are able to initiate an allogeneic...
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