Article
Effect of retroviral transduction on human endothelial cell phenotype and adhesion to Dacron vascular grafts.
Journal of vascular surgery - 1 Oct 1997
Jankowski R J, Severyn D A, Vorp D A, Wagner W R
Abstract excerpt
PURPOSE: Retroviral transduction for genetic enhancement of endothelial cell (EC) anti-thrombotic phenotype offers potential for improving the clinical success of vascular graft seeding; however, application of this technique may bring concomitant alteration in cell functionality. METHODS: Human...
Topics
- Blood Platelets
- Blood Vessel Prosthesis
- Cell Adhesion
- Cells, Cultured
- Endothelium, Vascular
- Flow Cytometry
- Gene Transfer Techniques
- Genetic Vectors
- Humans
- Intercellular Adhesion Molecule-1
- Neutrophils
- Phenotype
- Polyethylene Terephthalates
- Retroviridae
- Thromboplastin
- Transduction, Genetic
- beta-Galactosidase
