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Article

Resting B cells from New Zealand Black mice demonstrate a defect in apoptosis induction following surface IgM ligation.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 1996

Kozono Y, Kotzin B L, Holers V M

Abstract excerpt

New Zealand Black (NZB) mice spontaneously develop autoimmune disease, usually characterized by an autoimmune hemolytic anemia, and NZB genes are essential for a severe systemic lupus-like disease in (NZB x NZW)F1 mice. We have found that resting B cells from NZB mice demonstrate a pronounced defect, compared with five normal strains, in apoptosis induction after cross-linking with anti-IgM Abs. In contrast,...

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PMID: 8666826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Resting B cells from New Zealand Black mice demonstrate a defect in apoptosis induction following surface IgM ligation.PMID 8666826Read ↗

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A defective NF-kappa B/RelB pathway in autoimmune-prone New Zealand black mice is associated with inefficient expansion of thymocyte and dendritic cells.Semantic proximity Read ↗

CD4+ T lymphocytes with constitutive CD40 ligand in preautoimmune (NZB x NZW)F1 lupus-prone mice: phenotype and possible role in autoreactivity.Semantic proximity Read ↗

Distinct surface phenotypes of B cells responsible for spontaneous production of IgM and IgG anti-DNA antibodies in autoimmune-prone NZB x NZW F1 mice.Semantic proximity Read ↗

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