Article
Identification of a lupus-susceptibility locus leading to impaired clearance of apoptotic debris on New Zealand Black chromosome 13.
Genes and immunity - 1 Apr 2013
Pau E, Loh C, Minty G E S, Chang N-H, Wither J E
Abstract excerpt
Systemic lupus erythematosus is a chronic multi-organ autoimmune disease marked mainly by the production of anti-nuclear antibodies. Nuclear antigens become accessible to the immune system following apoptosis and defective clearance of apoptotic debris has been shown in several knockout mouse mod...
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