Article
Mapping the mouse dactylaplasia mutation, Dac, and a gene that controls its expression, mdac.
Genomics - 20 Sept 1995
Johnson K R, Lane P W, Ward-Bailey P, Davisson M T
Abstract excerpt
Dactylaplasia is an inherited mouse limb malformation whose manifestation is clearly dependent on the interaction of two genes and thus represents an excellent model system for studying such gene interactions in vivo. The Dac mutation is inherited as a semidominant trait and may be a model for some forms of human ectrodactyly. Heterozygotes show absence of digits on each foot; the long bones are normal. On the...
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