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Article

Characterization of mouse Dactylaplasia mutations: a model for human ectrodactyly SHFM3.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2008

Friedli Marc, Nikolaev Sergey, Lyle Robert, Arcangeli Mélanie, Duboule Denis, Spitz François, Antonarakis Stylianos E

Abstract excerpt

SHFM3 is a limb malformation characterized by the absence of central digits. It has been shown that this condition is associated with tandem duplications of about 500 kb at 10q24. The Dactylaplasia mice display equivalent limb defects and the two corresponding alleles (Dac1j and Dac2j) map in the region syntenic with the duplications in SHFM3. Dac1j was shown to be associated with an insertion of an unspecified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18392654
DOI: 10.1007/s00335-008-9106-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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