Article
The pel1 mutant of Saccharomyces cerevisiae is deficient in cardiolipin and does not survive the disruption of the CHO1 gene encoding phosphatidylserine synthase.
FEMS microbiology letters - 15 Jun 1996
Janitor M, Obernauerová M, Kohlwein S D, Subík J
Abstract excerpt
Cells of the pel1 mutant of Saccharomyces cerevisiae were found to contain an extremely low content of cardiolipin, a decreased level of phosphatidylcholine and an increased level of phosphatidylinositol. Disruption of the PEL1 gene in cells containing a null mutation in the CHO1 gene was lethal....
Topics
- Antigens
- CDPdiacylglycerol-Serine O-Phosphatidyltransferase
- Cardiolipins
- Fungal Proteins
- Genes, Fungal
- Lipid Metabolism
- Microtubule-Associated Proteins
- Mutation
- Phenotype
- Phosphatidylserines
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins