Article
Depletion of phosphatidylcholine in yeast induces shortening and increased saturation of the lipid acyl chains: evidence for regulation of intrinsic membrane curvature in a eukaryote.
Molecular biology of the cell - 1 Feb 2006
Boumann Henry A, Gubbens Jacob, Koorengevel Martijn C, Oh Chan-Seok, Martin Charles E, Heck Albert J R, Patton-Vogt Jana, Henry Susan A, de Kruijff Ben, de Kroon Anton I P M
Abstract excerpt
To study the consequences of depleting the major membrane phospholipid phosphatidylcholine (PC), exponentially growing cells of a yeast cho2opi3 double deletion mutant were transferred from medium containing choline to choline-free medium. Cell growth did not cease until the PC level had dropped...
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