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Article

Phosphatidylcholine Supply to Peroxisomes of the Yeast Saccharomyces cerevisiae.

PloS one - 1 Jan 2015

Flis Vid V, Fankl Ariane, Ramprecht Claudia, Zellnig Günther, Leitner Erich, Hermetter Albin, Daum Günther

Abstract excerpt

In the yeast Saccharomyces cerevisiae, phosphatidylcholine (PC), the major phospholipid (PL) of all organelle membranes, is synthesized via two different pathways. Methylation of phosphatidylethanolamine (PE) catalyzed by the methyl transferases Cho2p/Pem1p and Opi3p/Pem2p as well as incorporation of choline through the CDP (cytidine diphosphate)-choline branch of the Kennedy pathway lead to PC formation. To...

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Identifiers

PMID: 26241051
DOI: 10.1371/journal.pone.0135084
PMCID: PMC4524607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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