Article
Phosphatidylserine decarboxylase from Saccharomyces cerevisiae. Isolation of mutants, cloning of the gene, and creation of a null allele.
The Journal of biological chemistry - 5 Oct 1993
Trotter P J, Pedretti J, Voelker D R
Abstract excerpt
Phosphatidylserine decarboxylase plays a pivotal role in the synthesis of phospholipid by the mitochondria. The substrate phosphatidylserine is synthesized extramitochondrially and must be translocated to the mitochondria prior to decarboxylation. To understand the properties of the decarboxylase...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Carboxy-Lyases
- Chromosome Mapping
- Chromosomes, Fungal
- Cloning, Molecular
- DNA, Fungal
- Genes, Fungal
- Molecular Sequence Data
- Mutation
- Phenotype
- Saccharomyces cerevisiae
- Sequence Homology, Amino Acid