A polygenic model of inherited predisposition to cancer.

doi:10.1096/fasebj.10.8.8666163

Back to search

Article

A polygenic model of inherited predisposition to cancer.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jun 1996

Dragani T A, Canzian F, Pierotti M A

Abstract excerpt

Polygenic inheritance of predisposition to cancer is demonstrated in experimental animals for different tumor types. Genetic susceptibility to hepatocarcinogenesis, lung tumorigenesis, skin and intestine carcinogenesis, and plasmacytomagenesis is determined by inheritance of multiple cancer predi...

Topics

Animals
Forecasting
Genetic Predisposition to Disease
Humans
Models, Genetic
Neoplasms

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.