Article
[Molecular changes in adenocarcinoma of the small intestine associated with Peutz-Jeghers syndrome].
Revista espanola de enfermedades digestivas - 1 Feb 1996
Hidalgo L, Villanueva A, Soler T, Matías Guiu X, Capellá G
Abstract excerpt
The presence of molecular alterations in the c-K-ras and p53 genes in a small bowel adenocarcinoma arising in a case of Peutz-Jeghers syndrome is reported. The absence of mutations at codon 12 and 13 of the c-K-ras gene in the hamartoma and carcinoma indicates that this oncogene does not contribu...
Topics
- Adenocarcinoma
- Base Sequence
- Codon
- Genes, p53
- Genes, ras
- Humans
- Ileal Neoplasms
- Jejunal Neoplasms
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Peutz-Jeghers Syndrome
- Polymerase Chain Reaction