Article
Characterization of yeast methyl sterol oxidase (ERG25) and identification of a human homologue.
The Journal of biological chemistry - 12 Jul 1996
Li L, Kaplan J
Abstract excerpt
A yeast mutant (LT06) was isolated that showed no growth on iron-limited medium but normal growth on iron-replete medium. A gene cloned from a genomic yeast library complemented the defect, allowing growth on low iron medium. Allelic segregation analysis demonstrated that the cloned gene was the normal allele rather than a high copy suppressor. A disruption mutant was nonviable, indicating that the gene was...
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