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Article

Silencing of the Gene for the β Subunit of Human Chorionic Gonadotropin by the Embryonic Transcription Factor Oct-3/4

1 Jul 1996

Abstract excerpt

The transcription factor Oct-3/4 may be important in maintaining embryonic cells in an undifferentiated state. It is probably down-regulated at about the time that human chorionic gonadotropin (hCG) is first expressed in embryonic trophectoderm. Here we report that Oct-3/4 strongly inhibits the hCGbeta subunit (hCGbeta) promoter in JAr choriocarcinoma cells. Oct-3/4 reduced chloramphenicol acetyltransferase (CAT)...

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Identifiers

PMID: 8663260
DOI: 10.1074/jbc.271.28.16683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Silencing of the Gene for the β Subunit of Human Chorionic Gonadotropin by the Embryonic Transcription Factor Oct-3/4PMID 8663260Read ↗

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