Regulation of Chorionic Gonadotropin Gene Expression*

Abstract excerpt

CHORIONIC gonadotropin (CG) is a placental hormone that maintains the corpus luteum of pregnancy. Because CG is expressed at high levels soon after fertilization and implantation, it is used to detect pregnancy at early stages and to monitor the progress of pregnancy during the first trimester (1). CG is also produced in trophoblastic disease and in a variety of different malignancies, and it is useful as a tumor...