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Article

Oct-1 Binds Promoter Elements Required for Transcription of the GnRH Gene

1 Apr 1998

Abstract excerpt

The GnRH gene is exclusively expressed in a discrete population of neurons in the hypothalamus. The promoter-proximal 173 bp of the rat GnRH gene are highly conserved through evolution and are bound by multiple nuclear proteins found in the neuronal cell line, GT1-7, a model for the GnRH-expressing hypothalamic neuron. To explore the protein-DNA interactions that occur within this promoter and the role of these...

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Identifiers

PMID: 9544983
DOI: 10.1210/mend.12.4.0092

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