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Article

Characterization of a Ku86 variant protein that results in altered DNA binding and diminished DNA-dependent protein kinase activity.

The Journal of biological chemistry - 14 Jun 1996

Han Z, Johnston C, Reeves W H, Carter T, Wyche J H, Hendrickson E A

Abstract excerpt

Three proteins known to play a critical role in mammalian DNA double-strand break repair and lymphoid V(D)J recombination are the autoantigens Ku86 and Ku70 and a 465-kDa serine/threonine protein kinase catalytic subunit (DNA-PKcs). These proteins physically associate to form a complex (DNA.PK) w...

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Identifiers

PMID: 8662896
DOI: 10.1074/jbc.271.24.14098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8662896-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Characterization of a Ku86 variant protein that results in altered DNA binding and diminished DNA-dependent protein kinase activity.PMID 8662896Read ↗

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