Article
Functional characterization of two 5-HT3 receptor splice variants isolated from a mouse hippocampal cell line.
Pflugers Archiv : European journal of physiology - 1 May 1996
Glitsch M, Wischmeyer E, Karschin A
Abstract excerpt
Two splice variants of the ligand-gated 5-hydroxytryptamine or serotonin 5-HT3 receptor that differ in a six-amino-acid deletion were cloned by polymerase chain reaction from the hippocampus x neuroblastoma cell line HN9.10e. When expressed in Xenopus oocytes, both variants individually formed 5-HT3 receptors that revealed no significant differences in current responses to the agonists 5-HT and 1-phenylbiguanide...
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