Article
Gain-of-function alleles of Bearded interfere with alternative cell fate decisions in Drosophila adult sensory organ development.
Developmental biology - 15 Jun 1996
Leviten M W, Posakony J W
Abstract excerpt
We have isolated a novel class of gain-of-function mutations at the Bearded (Brd) locus which specifically affect the development of adult sensory organs in Drosophila. These Brd alleles cause bristle multiplication and bristle loss phenotypes resembling those described for the neurogenic genes Notch (N) and Delta (Dl). We have found that supernumerary sensory organ precursor (SOP) cells develop in the proneural...
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